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Anti -Vanilloid Receptor Like Protein 3 (Vanilloid Receptor-like 3, VRL 3, VRL-3, VRL3, HGNC:18084, Transient Receptor Potential Cation Channel Subfamily V Member 3, Trpv3 Heat Sensitive Channel, TRPV3)
Anti -Vanilloid Receptor Like Protein 3 (Vanilloid Receptor-like 3, VRL 3, VRL-3, VRL3,
HGNC:18084, Transient Receptor Potential Cation Channel Subfamily V Member 3, Trpv3 Heat
Sensitive Channel, TRPV3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
E IH |
|
| Vanilloid Receptor-like 3 (VRL-3), also known as transient receptor potential cation channel subfamily V3 (TRPV3) is a 70kD member of the vanilloid receptor/TRP gene family. It is expressed on keratinocytes and neurons, and is physiologically responsive to changes in temperature between 22° C and 40°C. Human TRPV3 is 790 amino acids (aa) in length. It is a 6 transmembrane domain protein that contains an N- and C-terminal cytoplasmic region. Three ankyrin repeats occur in the extended N-terminal cytoplasmic region (aa214-369). There is one alternate splice form that shows a 6aa substituton for the C-terminal 31 amino acids. Over amino acids 6-15, human TRPV3 shares 90% aa sequence identity with mouse and canine TRPV3. | | | Catalog # | V2075-28 | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: 5-15ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | ~0.2mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa6-15 of human Vanilloid Receptor-like 3, conjugated to KLH (Q8NET8). Species Sequence Homology: mouse and canine, 90% | | Specificity | Recognizes human Vanilloid Receptor-like 3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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