Vascular Endothelial Growth Factor B, aa22-207, Recombinant, Human (VEGFB, VEGF-B,
VEGF-related Factor, VRF)
Pricing
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| VEGF-B, also known as Vascular endothelial growth factor-B, is one of 5 mammalian VEGF family members, the others being VEGF-A, VEGF-C, VEGF-D, and placental growth factor (PlGF). VEGF-B binds to one of the VEGF receptor tyrosine kinases, namely VEGF receptor-1(VEGFR1, Flt1), but not to VEGFR2 and VEGFR3. VEGF-B is homodimeric, heparin-binding glycoprotein involved in embryonic angiogenesis and vasculogenesis. Recombinant VEGF-B protein was expressed in E. coli and purified by using conventional chromatography techniques. | | | Catalog # | V2110-04B | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MPVSQPDAPG HQRKVVSWID VYTRATCQPR EVVVPLTVEL MGTVAKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT PHHRPQPRSV PGWDSAPGAP SPADITHPTP APGPSAHAAP STTSALTPGP AAAAADAAAS SVAKGGA | | Biological Activity | Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 fro this effect is <1ng/ml | | Storage and Stability | Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 21.6kD | | Source | E. coli | | Purity | 90% (SDS-PAGE) Endotoxin: 1.0EU/1ug (LAL). | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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