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You are here:Home » Growth Factors, Cytokines » Growth Factors-VEGF » Vascular Endothelial Growth Factor B, aa22-207, Recombinant, Human (VEGFB, VEGF-B, VEGF-related Factor, VRF)

Vascular Endothelial Growth Factor B, aa22-207, Recombinant, Human (VEGFB, VEGF-B,
VEGF-related Factor, VRF)

Pricing

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Specifications

VEGF-B, also known as Vascular endothelial growth factor-B, is one of 5 mammalian VEGF family members, the others being VEGF-A, VEGF-C, VEGF-D, and placental growth factor (PlGF). VEGF-B binds to one of the VEGF receptor tyrosine kinases, namely VEGF receptor-1(VEGFR1, Flt1), but not to VEGFR2 and VEGFR3. VEGF-B is homodimeric, heparin-binding glycoprotein involved in embryonic angiogenesis and vasculogenesis. Recombinant VEGF-B protein was expressed in E. coli and purified by using conventional chromatography techniques.
Catalog #V2110-04B
AA SequenceMGSSHHHHHH SSGLVPRGSH MPVSQPDAPG HQRKVVSWID VYTRATCQPR EVVVPLTVEL MGTVAKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT PHHRPQPRSV PGWDSAPGAP SPADITHPTP APGPSAHAAP STTSALTPGP AAAAADAAAS SVAKGGA
Biological ActivityMeasured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 fro this effect is <1ng/ml
Storage and StabilityAliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight21.6kD
SourceE. coli
Purity90% (SDS-PAGE) Endotoxin: 1.0EU/1ug (LAL).
Concentration~1mg/ml
FormSupplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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