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You are here:Home » Growth Factors, Cytokines » Growth Factors-VEGF » Vascular Endothelial Growth Factor-121, Recombinant, Human, aa207-327 (VEGF-121)

Vascular Endothelial Growth Factor-121, Recombinant, Human, aa207-327 (VEGF-121)

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Specifications

Vascular endothelial growth factor (VEGF) is homodimeric, heparin-binding glycoprotein involved in both angiogenesis and vasculogenesis. VEGF is expressed as multiple alternately spliced isoforms of VEGF121, 165, 189 and 206. VEGF binds to the receptor tyrosine kinases VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1) to activate signal transduction and regulate both physiological and pathological angiogenesis.
Catalog #V2110-04E
Sequence of amino acidsMGSSHHHHHH SSGLVPRGSH MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV
Molecular Weight 16.3kD (142aa)
Endotoxin 1.0 EU/ug of protein (determined by LAL method)
Storage and StabilityFor long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight16.3kD
SourceE. coli
Purity90% by SDS PAGE. Recombinant VEGF121 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris pH 8.0.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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