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Anti -Vascular Endothelial Growth Factor C (VEGFC, Flt4-L, Flt4 ligand, Vascular endothelial growth factor-related protein, VEGF-C, VRP)
Anti -Vascular Endothelial Growth Factor C (VEGFC, Flt4-L, Flt4 ligand, Vascular
endothelial growth factor-related protein, VEGF-C, VRP)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| Vascular endothelial growth factor C is a VEGF. The human gene encoding it is VEGFC. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D (VEGF-D). | | | Catalog # | V2110-04W | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 0.5-1ug/ml. Detect human VEGF-C. The detection limit for rhVEGF-C is ~2.5ng/well. | | Western Blot: 0.1-0.2ug/ml Detection limit for rhVEGF-C is ~5ng/lane under non-reducing and reducing conditions. | | Immunohistochemistry: 5-15ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a lyophilized powder from PBS, pH 7.2, 5% trehalose. Reconstitute with 1ml sterile PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant human VEGF C, aa104-330 expressed in E. coli. | | Specificity | Recognizes human Vascular Endothelial Growth Factor C. | | Species Crossreactivity | <1% with rhVEGF-D and rhVEGF-A. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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