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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Vascular Endothelial Growth Factor C (VEGFC, Flt4-L, Flt4 ligand, Vascular endothelial growth factor-related protein, VEGF-C, VRP)

Anti -Vascular Endothelial Growth Factor C (VEGFC, Flt4-L, Flt4 ligand, Vascular
endothelial growth factor-related protein, VEGF-C, VRP)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Vascular endothelial growth factor C is a VEGF. The human gene encoding it is VEGFC. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D (VEGF-D).
Catalog #V2110-04W
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 0.5-1ug/ml. Detect human VEGF-C. The detection limit for rhVEGF-C is ~2.5ng/well.
Western Blot: 0.1-0.2ug/ml Detection limit for rhVEGF-C is ~5ng/lane under non-reducing and reducing conditions.
Immunohistochemistry (paraffin): 5-15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a lyophilized powder from PBS, pH 7.2, 5% trehalose. Reconstitute with 1ml sterile PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human VEGF C, aa104-330 expressed in E. coli.
SpecificityRecognizes human Vascular Endothelial Growth Factor C.
Species Crossreactivity<1% with rhVEGF-D and rhVEGF-A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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