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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF)

Anti -VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified N
VEGF (Vascular Endothelial Growth Factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeablility inducing properties specific for the vascular endothelium. Multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues have been described which arise from alternative splicing of a single gene. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell-associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Catalog #V2110-13
ApplicationsSuitable for use in Neutralization of the bioactivity of human VEGF. Other applications have not been tested.
Recommended DilutionNeutralization: Azide removal is required prior to use.
Optimal dilutions to be determined by the researcher.
Positive ControlAngiosarcoma
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No0.N.600
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide, before the addition of glycerol to 40%. Available without BSA and sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human VEGF121. Cellular Localization
SpecificityRecognizes human Vascular Endothelial Growth Factor (VEGF). Epitope has not been determined. Species Crossreactivity: Rabbit.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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