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You are here:Home » Molecular Biology » Growth Factors-VEGF » Vascular Endothelial Growth Factor 165, Recombinant, Human (VEGF 165)

Vascular Endothelial Growth Factor 165, Recombinant, Human (VEGF 165)

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VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Catalog #V2110-15J
Biological ActivityFully biologically active when compared to standard. Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0ng/ml.
Endotoxin 1EU/ug as determined by LAL method.
Storage and StabilityStore lyophilized powder dessicated at 20°C. Upon reconstitution, the preparation is stable for up to one week at 4°C. For maximal stability, store the reconstituted preparation at -20°C to -70°C. Avoid repeated freeze/thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight38.2 kD
SourceEscherichia coli
Purity~95% by SDS-PAGE and HPLC analyses.
Concentration1mg/ml
FormSupplied as a lyophilized powder in PBS, pH 7.5. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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