Anti -Vascular Endothelial Growth Factor Receptor 2 (VEGF Receptor 2, VEGFR 2, VEGFR2,
VEGFR-2, VEGFR, CD309 Antigen, Fetal Liver Kinase 1, FLK1, Kinase Insert Domain Receptor,
KDR, KRD1, Ly73, Protein Tyrosine Kinase Receptor FLK1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH IF |
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| VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signaling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. | | | Catalog # | V2110-18T3 | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:50-1:100 | | Western Blot: 1:500-1:2000 | | Immunohistochemistry (Frozen, paraffin): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Angiosarcoma | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, sodium azide. | | Purity | Purified by affinity chromatography | | Immunogen | Synthetic peptide derived from the C-terminus of the precursor form of the mouse Vascular Endothelial Growth Factor Receptor 2. Cellular Localization: Type I membrane protein. | | Specificity | Recognizes mouse Vascular Endothelial Growth Factor Receptor 2 at ~180kD. Species Crossreactivity: human, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Vascular Endothelial Growth Factor Receptor 2 (VEGF Receptor 2, VEGFR 2, VEGFR2, VEGFR-2, VEGFR, CD309 Antigen, Fetal Liver Kinase 1, FLK1, Kinase Insert Domain Receptor, KDR, KRD1, Ly73, Protein Tyrosine Kinase Receptor FLK1) |
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