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You are here:Home » Antibodies » Abs to Peptides » Anti -Vasoactive Intestinal Peptide (VIP)

Anti -Vasoactive Intestinal Peptide (VIP)

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Specifications

Clone Host Grade Applications
Polyclonal Guinea pig Serum IH IF
VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Catalog #V2115-06
ApplicationsSuitable for use in Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunofluorescence: 1:1000-1:2000 with overnight incubation at 4°C
Immunohistochemistry: Frozen and paraffin sections
Optimal dilutions to be determined by the researcher.
Positive ControlStefanini-fixed frozen sections of rat intestine.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGuinea pig
SourceHuman
ConcentrationNot Determined
FormSupplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O. Further dilutions can be made in PBS, 1% BSA, 0.1% sodium azide.
PuritySerum
ImmunogenSynthetic human VIP.
SpecificityRecognizes human VIP. Absorption with 10-100ug immunogen/ml diluted antiserum abolishes the staining, while PHI does not. Species Crossreactivity: porcine, feline, rabbit, rat, guinea pig.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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