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Anti -Vasoactive Intestinal Peptide (VIP)
Anti -Vasoactive Intestinal Peptide (VIP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Guinea pig |
Serum |
IH IF |
|
| VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas. | | | Catalog # | V2115-06 | | Applications | Suitable for use in Immunofluorescence and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunofluorescence: 1:1000-1:2000 with overnight incubation at 4°C | | Immunohistochemistry: Frozen and paraffin sections | | Optimal dilutions to be determined by the researcher. | | Positive Control | Stefanini-fixed frozen sections of rat intestine. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Guinea pig | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O. Further dilutions can be made in PBS, 1% BSA, 0.1% sodium azide. | | Purity | Serum | | Immunogen | Synthetic human VIP. | | Specificity | Recognizes human VIP. Absorption with 10-100ug immunogen/ml diluted antiserum abolishes the staining, while PHI does not. Species Crossreactivity: porcine, feline, rabbit, rat, guinea pig. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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