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You are here:Home » Antibodies » Abs to Peptides » Anti -Vasoactive Intestinal Peptide (VIP, MGC13587, PHM27)

Anti -Vasoactive Intestinal Peptide (VIP, MGC13587, PHM27)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Vasoactive intestinal peptide (VIP) is a 28aa peptide that exerts wide-ranging effects in embryonic and adult tissues through interactions with the 7-transmembrane spanning receptors VIP R1 and VIP R2. The VIP proprotein is proteolytically processed to release bioactive VIP as well as the bioactive peptides PHV and PHM. VIP regulates appetite and feeding behavior and stimulates insulin and glucagon secretion in pancreatic islet cells. It also regulates astrocyte function, multiple aspects of cardiac function, and TLR function in innate immune responses. Mature VIP shares 100% aa sequence identity with mouse and rat VIP.
Catalog #V2115-09A
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: 25ug/ml detects VIP in paraffin-embedded human normal and stomach cancer tissue sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C63
HostMouse
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptides corresponding to aa125-136 and aa145-152 from human VIP precursor protein (P01282). Species Sequence Homology: mouse and rat, 100%
SpecificityRecognizes human VIP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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