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You are here:Home » Antibodies » Abs to Receptors » Anti -Vasoactive Intestinal Polypeptide Receptor 1 (Vasoactive Intestinal Peptide Receptor 1, Vasoactive Intestinal Polypeptide Receptor 1 Precursor, VIP Receptor 1, VIP R 1, VIPR 1, VIPR1, VIP-R-1, VIP Receptor Type I, VIPR, FLJ41949, HVR1, Pituitary Adenylate

Anti -Vasoactive Intestinal Polypeptide Receptor 1 (Vasoactive Intestinal Peptide Receptor
1, Vasoactive Intestinal Polypeptide Receptor 1 Precursor, VIP Receptor 1, VIP R 1, VIPR
1, VIPR1, VIP-R-1, VIP Receptor Type I, VIPR, FLJ41949, HVR1, Pituitary Adenylate

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH FC
The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide; a small neuropeptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.
Catalog #V2115-20N1
ApplicationsSuitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1-10ug/ml. Detects a band at ~ 52kD.
Immunohistochemistry: Paraformaldehyde fixed sections
Optimal dilutions to be determined by the researcher.
Positive ControlA431 Whole Cell Lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS NumberN/A
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9F490
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.08% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant full length human Vasoactive Intestinal Polypeptide Receptor 1. Cellular Localization: Cell Membrane.
SpecificityRecognizes human Vasoactive Intestinal Polypeptide Receptor 1 at ~52kD. Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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