Anti -Vasoactive Intestinal Polypeptide Receptor 1 (Vasoactive Intestinal Peptide Receptor 1, Vasoactive Intestinal Polypeptide Receptor 1 Precursor, VIP Receptor 1, VIP R 1, VIPR 1, VIPR1, VIP-R-1, VIP Receptor Type I, VIPR, FLJ41949, HVR1, Pituitary Adenylate
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH FC |
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| The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide; a small neuropeptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. | | | Catalog # | V2115-20N1 | | Applications | Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Western Blot: 1-10ug/ml. Detects a band at ~ 52kD. | | Immunohistochemistry: Paraformaldehyde fixed sections | | Optimal dilutions to be determined by the researcher. | | Positive Control | A431 Whole Cell Lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 9F490 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.08% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant full length human Vasoactive Intestinal Polypeptide Receptor 1. Cellular Localization: Cell Membrane. | | Specificity | Recognizes human Vasoactive Intestinal Polypeptide Receptor 1 at ~52kD. Species Crossreactivity: rat | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Vasoactive Intestinal Polypeptide Receptor 1 (Vasoactive Intestinal Peptide Receptor 1, Vasoactive Intestinal Polypeptide Receptor 1 Precursor, VIP Receptor 1, VIP R 1, VIPR 1, VIPR1, VIP-R-1, VIP Receptor Type I, VIPR, FLJ41949, HVR1, Pituitary Adenylate |
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