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Anti -Vaspin, Recombinant, Human (Visceral Adipose-Specific SERPIN, SERPINA12, Serine proteinase inhibitor-clade A12) (Biotin)
Anti -Vaspin, Recombinant, Human (Visceral Adipose-Specific SERPIN, SERPINA12, Serine
proteinase inhibitor-clade A12) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| Serine proteinase inhibitor-clade A12; also vaspin) is a 45-50kD secreted member of the alpha1-antitrypsin (clade A)-subfamily, Serpin superfamily of protease inhibitors. It is produced by visceral adipocytes, and adipocyte-derived stem cells during obesity or diabetes. The presence of vaspin reverses insulin-resistance. Its molecular target is unknown. Human Serpin A12 is 414 amino acids (aa) in length. It contains a 20 aa signal sequence and a 394 aa mature region. A potential “active” inhibitor site lies between Arg363 and Met378. Mature human Serpin A12 shares 61% aa identity with mouse Serpin A12. | | | Catalog # | V2118-10B | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.1-0.2ug/ml detection limit for rhSerpin A12 is ~ 5ng/lane under non-reducing and reducing conditions. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in Tris, pH 7.3, 1% BSA. Reconstitute with 1ml sterile 40-50% glycerol, Tris, 0.1mg/ml BSA. Labeled with Biotin. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | NS0-derived rhSerpin A12. (aa 20 - 414) | | Specificity | Recognizes human Serpin A12. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Serine Proteinase Inhibitor-Clade A#12 |
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