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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Vaspin, Recombinant, Human (Visceral Adipose-Specific SERPIN, SERPINA12, Serine proteinase inhibitor-clade A12) (Biotin)

Anti -Vaspin, Recombinant, Human (Visceral Adipose-Specific SERPIN, SERPINA12, Serine
proteinase inhibitor-clade A12) (Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Affinity Purified B
Serine proteinase inhibitor-clade A12; also vaspin) is a 45-50kD secreted member of the alpha1-antitrypsin (clade A)-subfamily, Serpin superfamily of protease inhibitors. It is produced by visceral adipocytes, and adipocyte-derived stem cells during obesity or diabetes. The presence of vaspin reverses insulin-resistance. Its molecular target is unknown. Human Serpin A12 is 414 amino acids (aa) in length. It contains a 20 aa signal sequence and a 394 aa mature region. A potential “active” inhibitor site lies between Arg363 and Met378. Mature human Serpin A12 shares 61% aa identity with mouse Serpin A12.
Catalog #V2118-10B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-0.2ug/ml detection limit for rhSerpin A12 is ~ 5ng/lane under non-reducing and reducing conditions.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in Tris, pH 7.3, 1% BSA. Reconstitute with 1ml sterile 40-50% glycerol, Tris, 0.1mg/ml BSA. Labeled with Biotin.
PurityPurified by immunoaffinity chromatography.
ImmunogenNS0-derived rhSerpin A12. (aa 20 - 414)
SpecificityRecognizes human Serpin A12.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSerine Proteinase Inhibitor-Clade A#12


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