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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -VAV1 (Vav 1, Vav 1 Oncogene, Vav-1, Vav-1 Oncogene, Oncogene Vav, p95-Vav, Proto oncogene Vav, Proto-oncogene Vav, Vav, Vav Proto oncogene, Vav proto-oncogene) (Azide Free)

Anti -VAV1 (Vav 1, Vav 1 Oncogene, Vav-1, Vav-1 Oncogene, Oncogene Vav, p95-Vav, Proto
oncogene Vav, Proto-oncogene Vav, Vav, Vav Proto oncogene, Vav proto-oncogene) (Azide
Free)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
Catalog #V2121-07C
ApplicationsSuitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No11C947
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to aa681-791 of human VAV1.
SpecificityRecognizes human VAV1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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