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Virginiamycin B
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| Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups leading to considerable confusion in the literature. Viriginiamycin B acts as a synergist binding to the conformational change in the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A. | | | Catalog # | V2122-82A | | Source | Vigriniamycin B from Streptomyces sp. | | Molecular Weight | ~867 | | Solubility | Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 3131-03-1 | | Molecular Formula | C45H54N8O10 | | Molecular Weight | ~867 | | Purity | ~99% (HPLC) | | Concentration | Not determined | | Form | Supplied as a white solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
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