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You are here:Home » Biochemicals » Biochem-Vitamins » 1a, 25-Dihydroxycholecalciferol, (1a,25-Dihydroxyvitamin D3, 25-(OH)2-D3, Calcitriol)

1a, 25-Dihydroxycholecalciferol, (1a,25-Dihydroxyvitamin D3, 25-(OH)2-D3, Calcitriol)


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An active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Known to act as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.
Catalog #V2129-01
Molecular Weight~416.6
SolubilityDMSO (50mg/ml), EtOH
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO or EtOH. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number32222-06-3
Molecular FormulaC H O
Molecular Weight~416.6
Purity~99% (HPLC)
ConcentrationNot determined
FormSupplied as a white powder. Reconstitute with DMSO or EtOH.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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