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You are here:Home » Antibodies » Abs to Receptors » Anti -Vitamin D Receptor (VDR, vitamin D (1,25- dihydroxyvitamin D3) receptor , HGNC:12679, NR1I1, vitamin D (1,25-dihydroxyvitamin D3) receptor)

Anti -Vitamin D Receptor (VDR, vitamin D (1,25- dihydroxyvitamin D3) receptor ,
HGNC:12679, NR1I1, vitamin D (1,25-dihydroxyvitamin D3) receptor)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Purified B IP IH IC Gel
VDR is a member of the super family of steroid hormone receptors. It is known to play a role in cellular growth and differentiation, calcium and phosphorus metabolism and bone remodeling. Human breast carcinomas, leukemias, and prostatic carcinoma cells express VDR, which can modify their growth and differentiation. Human breast carcinomas, leukemias, and prostatic carcinoma cells express VDR which can modify their growth and differentiation.
Catalog #V2130-01A
ApplicationsSuitable for use in Gel Supershift Assays, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin and frozen sections): 5ug/ml
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No6D831
HostRat
SourceChicken
Concentration~1mg/ml
FormSupplied as a liquid in 0.05% sodium azide.
PurityPurified
ImmunogenPartially purified chicken intestinal cytoplasmic VDR (vitamin D3 receptor).
SpecificityRecognizes the occupied and unoccupied forms of chicken VDR. Recognizes an epitope between aa 89 and 105 of human VDR. In avians detects bands of ~58kD and ~60kD by Western blot, while in mammalian species the VDRs appear as a single band within the ~52-55kD range. Does not cross-react with ER (estrogen receptor) or GR (glucocorticoid receptor). Species Crossreactivity: human, mouse, rat, hamster, amphibian and fish.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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