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You are here:Home » Antibodies » Abs to RNA Processing » Anti -VCX-A (Variable charge X-linked protein 3, Variably charged protein X-A, VCX-8r, Variable charge protein on X with eight repeats, VCX3A, VCX3, VCX8R, VCXA)

Anti -VCX-A (Variable charge X-linked protein 3, Variably charged protein X-A, VCX-8r,
Variable charge protein on X with eight repeats, VCX3A, VCX3, VCX8R, VCXA)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
VCX-A is only expressed in testis and may play a role in spermatogenesis or in sex ratio distortion. It is a 186aa peptide that has an estimated molecular weight of ~20kD. It was recently identified that VCX-A is an inhibitor of the decapping enzyme DCP2 and that it stabilized mRNA. It is a noncanonical cap-binding protein that binds to capped RNA but not cap structures lacking RNA. Defects in VCX-A are associated with some forms of X-linked nonspecific mental retardation.
Catalog #V3300
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G460
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant human VCX-A (aa2-100) with a GST tag.
SpecificityRecognizes VCX-A. Species Crossreactivity: human, mouse, and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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