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You are here:Home » Antibodies » Abs to Infectious Disease WNV » Anti -West Nile Virus

Anti -West Nile Virus

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IF
West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
Catalog #W1018-50K
ApplicationsSuitable for use in Immunofluorescence and ELISA. Other applications not tested.
Recommended DilutionsImmunofluorescence: 1:10-1:50
ELISA: 1:20-1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10D33
HostMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. No Stabilizing proteins added.
PurityPurified by Protein A affinity chromatography.
ImmunogenWest Nile Virus
SpecificityRecognizes the envelope protein. Has positive reactivity with WNV and SLE flaviviruses. Has a negative reaction with JEV, YFV, DEN, TBE, EEE, WEE, POW, LAC, VEE.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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