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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -Wnt1 (Proto-oncogene Wnt-1, Proto-oncogene Int-1 Homolog, INT1)

Anti -Wnt1 (Proto-oncogene Wnt-1, Proto-oncogene Int-1 Homolog, INT1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Wnt1, a 370aa protein belonging to the Wnt family, is a signaling molecule important in CNS development. It plays a role in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 signaling is involved in many functions including the inhibition of apoptosis in several cancers, inhibition of interfollicular progenitor cell growth and it promotes terminal differentiation of keratinocytes and plays a role in angiogenesis by endothelial cell growth control that is mediated through cell-cell contact. Wnt1 blockade by either monoclonal antibody or siRNA induces cell death in sarcoma cells. It is expressed in hair follicles, sebaceous glands, skin and other tissues.
Catalog #W3006-02D
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa275-288 (EPEDPAHKPPSPHD) of human Wnt1.
SpecificityRecognizes human Wnt1/Int1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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