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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -Wnt5A (Protein Wnt-5a)

Anti -Wnt5A (Protein Wnt-5a)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Wnt5A is a nontransforming member of the Wnt family of secreted and cysteine-rich proteins that exert their cellular effects via autocrine or paracrine routes. It is a proto-oncogene that functions in modulating cell fate and cell behavior during vertebrate development and has an important role in the Wnt signaling pathway. It acts as a ligand for members of the frizzled family of seven transmembrane receptors. The protein also plays a role in preventing metastatic disease in invasive breast carcinomas. The protein has many conserved features like a hydrophobic signal sequence, Wnt1 family signature sequence (CKCHGvSGSC), and a number of other conserved aa residues. Human Wnt5A expression was detected only in neonatal heart and lung. The gene for human Wnt5A is localized on chromosome 3p21-p14.
Catalog #W3028-01A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa274-295 ([BLAST]AMRLNSRGKLVQVNSRFNSPT[BLAST]) of human Wnt5A.
SpecificityRecognizes human Wnt5A. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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