Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Wnt Proteins » Anti -Wnt5A (Protein Wnt-5a)

Anti -Wnt5A (Protein Wnt-5a)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Wnt5A is a nontransforming member of the Wnt family of secreted and cysteine-rich proteins that exert their cellular effects via autocrine or paracrine routes. It is a proto-oncogene that functions in modulating cell fate and cell behavior during vertebrate development and has an important role in the Wnt signaling pathway. It acts as a ligand for members of the frizzled family of seven transmembrane receptors. The protein also plays a role in preventing metastatic disease in invasive breast carcinomas. The protein has many conserved features like a hydrophobic signal sequence, Wnt1 family signature sequence (CKCHGvSGSC), and a number of other conserved aa residues. Human Wnt5A expression was detected only in neonatal heart and lung. The gene for human Wnt5A is localized on chromosome 3p21-p14.
Catalog #W3028-01B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 5-10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa195-211 (EFVDARERERIHAKGSY) of human Wnt5A, (NP_003383).
SpecificityRecognizes human Wnt5A. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links