ZNF703

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Ca Hu Po

Accession #

NP_079345.1

Gene ID

80139

Shipping Temp

Blue Ice

Storage Temp

-20°C

Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution

ELISA: 1:32,000 Western Blot: 1-3ug/ml, observed in human breast cancer lysates on ~60kD bands Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to C-ELDKKDQEPKPSPE, from human ZNF703, at the internal region of the protein (NP_079345.1).

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes human ZNF703. Species sequence homology: Canine and porcine.

References

1. Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, Ozdag H, Vias M, Kranjac T, Subkhankulova T, Paish C, Ellis I, Brenton JD, Edwards PA, Caldas C. A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. Oncogene. 2005 Aug 4;24(33):5235-45.

USBio References

No references available

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Z0319-50B Goat Anti-ZNF703 (Zinc Finger Protein 703, Zinc Finger Elbow-related Proline Domain Protein 1, ZEPPO1, ZPO1)

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Crossreactivity

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