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Zearalenone (Zearalanol, Zearanol, Mycotoxin F2, Toxin F2, RAL)
Zearalenone (Zearalanol, Zearanol, Mycotoxin F2, Toxin F2, RAL)
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| Zearalenone is a phenolic resorcyclic acid lactone and can be produced by a number of species of Fusarium known to colonize cereals. Zearalenone (6-[10-hydroxy-6-oxo-trans-1-undecenyl]-b-resorcyclic acid lactone), also known as F-2 toxin, is an estrogenic mycotoxin that is produced by Fusarium graminearum. This fungus can infect cereal grains and can elaborate large quantities of zearalenone. | | | Catalog # | Z0400-10B | | Zearalenone is a naturally occurring estrogen, recognized as causing hormonal effects in animal species such as the pig. The association between zearalenone exposure and human diseases remains speculative at present; it has been considered as a possible causative agent in outbreaks of precocious pubertal changes in young children and has been suggested to have a possible involvement in human cervical cancer. | | Solubility | Limited solubility in water (~0.002g/100ml). Slightly soluble in hexane and progressively more in benzene, acetonitrile, dichloromethane, methanol, acetone. Produceds a clear, colorless solution at 5mg/ml in methanol. | | Melting Point | 167°C | | Lambda max (MeOH) | 235, 274, 313 nm | | Applications | The resorcylic acid lactones have estrogenic activity. Zearalenone and its derivates have been used as veterinary anabolic or estrogen substitutes. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stale for 12 months. Reconstitute with methanol. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 17924-92-4 | | Molecular Formula | C18H22O5 | | Molecular Weight | 318.4 | | Source | Giberella zeae. | | Purity | ~ 98% by TLC, HPLC | | Form | Supplied as a white to off-white powder | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Mycotoxin F2, Toxin F2 |
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