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You are here:Home » Biologicals » Biologicals-Cells-Human Neural Progenitor » Neural Progenitor Cells, Human (hNPC), Donor F, Frozen Cells, Axol™

Neural Progenitor Cells, Human (hNPC), Donor F, Frozen Cells, Axol™


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Axol human neural progenitor cells (hNPCs, ax0011-ax0016) are derived from NIH approved induced pluripotent stem cell (iPSC) lines under a fully defined neural induction condition (Shi, Y. et al, 2012a, b, c). The hNPCs express typical markers of cortical neural stem and progenitor cells, and spontaneously form neural tube-like rosette structures when plated as a monolayer in culture (Fig. 2-6).
Catalog #ax0016
Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s disease, autism, epilepsy and stroke. Despite strong interest in these diseases, high quality human in vitro cell models for cortical neurophysiology were unavailable until now. With Axol hNPCs, we provide neuroscience researchers with a high quality in vitro human system to complement their existing studies of cortical development, function and diseases using animal models.
Advantages of Axol hNPCs• Human cells
• Available in industrial quantity
• High purity neural progenitor population
• Ready-made and easy to differentiate
• No reprogramming and differentiation needed
• Robust enough to undergo genetic manipulation
• Supplied with extensive functional and molecular characterization data
• Capable of differentiating to a spectrum of cortical excitatory and inhibitory neurons
• Remain viable in culture for months to facilitate reproducible and long term studies
• Cells from multiple donors are available for purchase allowing data comparison among biological replicates
Applications• Studying Corticogenesis in vitro
• Studying neural network formation and signal transmission 
• Disease modelling
• Neurotoxicity testing
• Preclinical drug efficacy testing
• Research and development of cell therapies in animal models
Specifications• Quantity: 2 million expandable cells per vial
• Presentation: Cells are provided cryopreserved in 1ml of freezing medium
• Storage Condition: Liquid nitrogen
• Growth Properties: Adherent
Donor AgeNewborn
Starting MaterialCord Blood CD34+ Cells
Reprogramming MethodEpisomal Plasmid
Neural Induction MethodMonolayer and Chemically-defined medium
Genetic ModificationNone
Size2 Million expandable cells per vial
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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