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Axol > hyCCNs Frozen

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Axol Human Cerebral Cortical Neurons
(Young hyCCNs Frozen)

Axol Human Cerebral Cortical Neurons, microtiter plate, and protocolAxol hCCNs are derived from integration-free, induced pluripotent stem (iPS) cells under fully defined neural induction conditions..

The neurons are cryopreserved in our proprietary freezing medium. After thawing and plating, the neurons terminally differentiate to acquire mature electrophysiological properties, and form functional synaptic network over a period of 40 ~ 50 days.

Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s disease, autism, epilepsy and stroke. Despite strong interest in these diseases, high quality human in vitro cell models for cortical neurophysiology have been unavailable until now. With Axol hCCNs, we provide neuroscience researchers with a high quality in vitro human system to complement their existing studies of cortical development, function and diseases using animal models.


Axol Cerebral Cortical Neurons fluorescent images


1 day after thawing

14 days after thawing

1 day thawed Axol Cerebral Cortical Neurons 14 days thawed Axol Cerebral Cortical Neurons 



Cat #

Product Name


Donor Age

Starting Material

Reprogramming Method

Neural Induction Method

Genetic Mod.


ax0025F hyCCN
Donor A
Male New Born Cord Blood CD34+ Cells Episomal Plasmid Monolayer
Chem-defined medium
No 2M Cells
frozen vials
ax0026F hyCCN
Donor A
Female New Born Cord Blood CD34+ Cells Episomal Plasmid Monolayer
Chem-defined medium
No 2M Cells
frozen vials


Advantages of Axol hyCCNs



  • Human cells
  • Available in industrial quantity
  • Ready-made
  • Supplied with extensive functional and molecular characterization data
  • Include a spectrum of cortical neurons
  • Remain viable in culture for months to facilitate reproducible and long term studies
  • Cells from multiple donors are available for purchase allowing data comparison among biological replicates
  • Quantity: 2 million cryopreserved young neurons
  • Presentation: Cells are provided cryopreserved in 1 ml of freezing medium
  • Storage Condition: Liquid nitrogen
  • Growth Properties: Adherent 
  • Studying Corticogenesis in vitro
  • Studying neural network formation and signal transmission  
  • Disease modelling
  • Neurotoxicity testing
  • Preclinical drug efficacy testing