|USBio Home||800-520-3011||Email USBio||Fax: 781-639-1768|
Material Safety Data Sheet
|USBio MSDS 1.0|
|1a. Identification of the substance/preparation|
Cat #: G9010
Product Name: Guanidine Hydrochloride
Alt. Name: Aminomethanamidine hydrochloride,Aminoformamidine hydrochloride, Carbamidine hydrochloride, Guanidine chloride, Guanidinium chloride, Guanidinium hydrochloride, Iminourea
CAS #: 50-01-1
Molecular Weight: 95.53
Molecular Formula: CH5N3•HCl
United States Biological
P.O. Box 261
Swampscott Ma, 01907
800-520-3011 Fax: 781-639-1768
|2. Hazards identification|
Toxic if swallowed. Irritating to eyes and skin.
Target organs: bone marrow, nerves
Health hazard: 2+
Health hazard: 2
For additional information on toxicity, please refer to section 11.
|3. Composition/ Information on ingredients|
Guanidine hydrochloride, ≥ 99.5%
|4. First-aid measures|
If swallowed, wash out mouth with water provided person is conscious. Call a physician. In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. Call a physician. If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
|5. Fire fighting measures|
Extinguishing media: carbon dioxide, dry chemical powder or appropriate foam
Special firefighting procedures: wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Specific hazards: emits toxic fumes under fire conditions.
|6. Accidental release measures|
Procedure to be followed in case of leak or spill: evacuate area Personal protection: wear self-contained breating apparatus, rubber boots, and heavy rubber gloves.
Methods for cleaning up; sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
|7. Handling and storage|
Handling: user exposure; do not breathe dust. Avoid contact with eyes, skin and clothing. Avoid prolonged or repeated exposure. Storage: keep tightly closed (this substance is hygroscopic).
|8. Exposure controls/personal protection|
Personal protective equipment: niosh/msha-approved respirator. Of tje respirator is the sole means of protection, use a full-face supplied air respirator. Compatible chemical-resistant gloves. Chemical safety goggles. Potentially biohazardous material.
Engineering controls: mechanical exhaust required. Safety shower and eye bath.
General hygiene measures: wash thoroughly after handling.
|9. Physical and chemical properties|
Purity: ≥ 99.5%
Appearance: white, crystalline powder
Melting point: 183-188°c
Solubility (4%, h2o): colorless, clear, complete
Ph of solution: 6.0±0.2
|10. Stability and reactivity|
Conditions to avoid: moisture
Materials to avoid: strong oxidizing agents
Hazardous decomposition products: carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen chloride gas
Hazardous polymerization: will not occur.
|11. Toxicological information|
Route of exposure
Skin contact: causes skin irritation.
Skin absorption: may be harmful if absorbed through the skin.
Eye contact: causes eye irritation.
Inhalation: may be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract. Ingestion: harmful if swallowed.
Target organ(s) or system(s): nerves. Bone marrow.
Signs and symptoms of exposure: to the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Conditions aggravated by exposure: may cause nervous system disturbances.
Oral: rat: 475 mg/kg ld50
Remarks: behavioral: altered sleep time (including change in righting reflex). Behavioral: excitement. Gastrointestinal: hypermotility, diarrhea.
Oral: mouse: 571 mg/kgld50
Remarks: behavioral: altered sleep time (including change in righting reflex). Behavioral: muscle contraction or spasticity. Behavioral:i rritability.
Intraperitoneal: mouse: 500 mg/kg ld50
Skin: rabbit: 500 mg, 24h. Remarks: severe irritation effect
Eyes: rabbit; 81.4mg. Remarks: moderate irritation effect
|12. Ecological information|
No data available.
|13. Disposal considerations|
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state and local environmental regulations.
|14. Transport information|
Proper shipping name: none
This substance is considered to be non-hazardous for transport.
This substance is non-hazardous for air transport.
|15. Regulatory information|
Eu directives classification:
Symbol of danger: xn
Indication of danger: harmful.
Risk statements: harmful if swallowed. Irritating to eyes and skin.
Safety statements: do not breathe dust.
Us classification and label text
Indication of danger: toxic (usa) harmful (eu).
Risk statements: toxic if swallowed. Irritating to eyes and skin.
Safety statements: in case of contact with eyes, rinse
Immediately with plenty of water and seek medical advice. Wear suitable protective clothing.
Us statements: target organ(s): bone marrow. Nerves.
United states regulatory information
Sara listed: no
Tsca inventory item: yes
Canada regulatory information
Whmis classification: this product has been classified in accordance with the hazard criteria of the cpr, and the msds contains all the information required by the cpr.
|16. Other information|
United States Biological provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. this document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. united states biological makes no representations or warranties, either express or implied, including without limitation any warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or the product to which the information refers. accordingly, united states biological will not be responsible for damages resulting from use of or reliance upon this information.