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Netrin-1 as a Novel Target in Atherosclerosis

 
 

NEW Products

 
 

Catalog #

Product Name

A0855-39G Activation Transcription Factor 1 phosphorylated (Ser63)
B1037B Bendamustine-d5 (major) Hydrochloride
B1083-49 Beta Lactam (HRP)
F4195-14 Fibrillin 3
R2031-15B Ribonucleotide Reductase
T9155-03R Tubulin, beta 3

 
 

SPECIAL Troponin

 
 

Troponin is a complex of three regulatory proteins (troponin C, troponin I and troponin T) that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle. Troponin, working in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in intracellular Ca2+ concentration.

chocolate mms forming a heart shape
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FEATURED Heartworm

 
 
dog with a heart-shaped spot on its torso

Heartworm is a parasitic roundworm (Dirofilaria immitis) that is spread from host to host through the bites of mosquitoes. The heartworm is a type of filaria, a small thread-like worm. The definitive host is the dog but it can also infect cats, wolves, coyotes, foxes and other animals, such as ferrets, sea lions and even, under very rare circumstances, humans. The parasite is commonly called 'heartworm' because the adult reproductive stage of its life cycle resides primarily in the right ventricle of its host where it can live for many years. Heartworm infection may result in serious disease for the host.

 

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ARTICLE Netrin-1 as a Novel Target in Atherosclerosis

 
 

A recent study has identified a new culprit that leads to atherosclerosis, the accumulation of fat and cholesterol that hardens into plaque and narrows arteries (1, 2). The research explains why cholesterol-laden, coronary artery disease-causing cells called macrophages, accumulate in artery plaques.

Atherosclerosis is a disease in which plaque builds up on the inside of arteries. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows the arteries. The flow of oxygen-rich blood to your organs and other parts of your body is reduced. This can lead to serious problems, including heart attack, stroke, or even death.

Catalog #

Product Name

Type

Host

Source

N1193-16 Netrin 1 (Netrin 1, Ntn1, NTN1L, Unc6) Pab Ch x Hu
N1193-18 Netrin 4 Pab Gt x  
U0893-50 UNC5C Pab Gt x Hu
U0893-50A UNC5C Pab Rb x Hu

 

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