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New Products

A1372-19A Anti-Alzheimer Precursor Protein A4 (N-terminus) (FITC)
A4159-04G ATX1 (Ataxin 1)
E3360-01L Eck/EphA2 (PE)
F4212-18 FGF14/FHF4, Fibroblast Growth Factor 14, Fibroblast Growth Factor Homologous Factor 4
G2035-07Q Git1 (ARF GTPase-activating protein GIT1)
G3500-12D GluR2 (Glutamate Receptor)
G8600-60B G Protein Coupled Receptor 56 (GPCR56, GPR56)
K9001-07D Kv1.2 (Kcna2, Voltage-gated Potassium Channel)

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April Deal: 10% Off GMO Kits

   Our Biogenomics™ GMO Real-time PCR Kits and Detection Kits are designed for the screening and detection of Genetically Modified Organisms in seed, crop, raw materials, and processed food. After DNA extraction using one of our Extraction Kits simply mix the extracted DNA with the Kit's reagents, do a PCR or Real-time PCR run, and analyze.The whole process takes only 4.5 hours.

G8235-67B GM Bt176 (GMO) Detection Kit, Real-time PCR, BioGenomics™
G8235-67M GM Bt176 (GMO) Real-time PCR Kit, BioGenomics™
G8235-68M GM CBH351, Starlink (GMO) Real-time PCR Kit, BioGenomics™
G8235-69B GM DAS59122-7 (GMO) Detection Kit, Real-time PCR, BioGenomics™
G8235-69M GM DAS59122-7 (GMO) Real-time PCR Kit, BioGenomics™

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Featured Product: Histones

Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different post-translational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.

H5110 Histone H1 Pab Sh xBo
H5110-01 Histone H1 Mab Mo xHu
H5110-03 Histone H1, phosphorylated Pab Rb x
H5110-10 Histone, Core Pab Sh xBo

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Featured Article: HERV's

The human genome contains about 8% of sequences of retroviral origin, remnants of different exogenous retrovirus infections of the germ line genome that occurred millions of years ago. Endogenous retroviruses may be a variant of a retrovirus that became permanently integrated with its host and is inherited from generation to generation as part of the genome of the host.

Retroviruses are single-stranded RNA viruses that reverse-transcribe their RNA into DNA for integration into the host's genome. Most retroviruses (such as HIV-1) infect somatic cells, but in very rare cases, it is thought that exogenous retroviruses have infected germline cells (cells that make eggs and sperm) allowing integrated retroviral genetic sequences to be passed on to subsequent offspring, thereby becoming 'endogenous'. Endogenous retroviruses have persisted in the genome of their hosts for thousands of years. However, they are generally only infectious for a short time after integration as they acquire many inactivating mutations during host DNA replication. They can also be partially excised from the genome by a process known as recombinational deletion. They are thought to play a key role in evolution.


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