December 2011

NEW Products

SPECIAL MagDetect™ 10% OFF 

MagDetect™-protein A and/or G beads can be used to detect or isolate target proteins by coupling the Fc domain of the IgG antibody for a target protein. The advantage of these beads compared to streptavidin beads is that the antibody does not need to be biotinylated.  These magnetic beads are ideal for protein isolation and proteomic applications.

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FEATURED Heparan Sulfate

Heparan sulfate, otherwise known as heparitin sulfate or heparin monosulfate, is a generic term describing polysaccharides which are linear and consist of N-acetylated [->4)alpha-D-GlcNpAc-(1->4)ß -D-GlcAp(1->] and N-sulfated disaccharides [->4)alpha-D-GlcNpS- (1->4)-ß-D-GlcAp or alpha-L-IdoAp(1->] that are arranged mainly in a segregated manner.

ARTICLE Stress-Activated Protein Kinase (SAPK)

To maximize the probability of survival, cells need to coordinate their intracellular activities in response to changes in the extracellular environment. MAP kinase cascades play an important role in the transduction of signals inside eukaryotic cells. In particular, stress stimuli result in the rapid activation of a highly conserved group of MAP kinases, known as SAPKs (Stress-Activated Protein Kinases). These kinases coordinate the generation of adaptive responses that are essential for cell survival, which include the modulation of several aspects of cell physiology from metabolism to gene expression.

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