CIB1, Recombinant, Human, aa1-191, His-Tag CAS

Grade

Highly Purified

Accession Number

NP_006375

Molecular Weight

EU Commodity Code

30021019

Shipping Temp

Blue Ice

Storage Temp

-20°C

CIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin alpha IIb, PAK1, and polo-like kinases, in different tissues.

Source

Recombinant protein corresponding to aa1-191 of human CIB1, fused to His-tag at N-terminal expressed in E. coli.

Molecular Weight

~23kD

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRTVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Source

Recombinant, E. coli

Purity

≥95% (SDS-PAGE)

Concentration

~1mg/ml

Form

Supplied as a liquid in 20mM Tris, pH 8.0, 5mM DTT.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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349788 CIB1, Recombinant, Human, aa1-191, His-Tag (Calcium and integrin binding 1, CIB, KIP, Kinase interacting protein, SIP2-28, SNK interacting protein2-28, Calmyrin) CAS:

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