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350168 PGM2, Recombinant, Human, aa1-612, His-Tag (Phosphoglucomutase-2) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_060760
Molecular Weight
70.7
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

PGM2 is also known as Phosphoglucomutase-2. PGM2 is protein of the alpha-d-phosphohexomutase family and sharing about 20% identity with mammalian phosphoglucomutase 1. It acts more than 10-fold better as a phosphopentomutase than as a phosphoglucomutase.

Source
Recombinant protein corresponding to aa1-6129 of human PGM2, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~70.7kD
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAPEGS GLGEDARLDQ ETAQWLRWDK NSLTLEAVKR LIAEGNKEEL RKCFGARMEF GTAGLRAAMG PGISRMNDLT IIQTTQGFCR YLEKQFSDLK QKGIVISFDA RAHPSSGGSS RRFARLAATT FISQGIPVYL FSDITPTPFV PFTVSHLKLC AGIMITASHN PKQDNGYKVY WDNGAQIISP HDKGISQAIE ENLEPWPQAW DDSLIDSSPL LHNPSASINN DYFEDLKKYC FHRSVNRETK VKFVHTSVHG VGHSFVQSAF KAFDLVPPEA VPEQKDPDPE FPTVKYPNPE EGKGVLTLSF ALADKTKARI VLANDPDADR LAVAEKQDSG EWRVFSGNEL GALLGWWLFT SWKEKNQDRS ALKDTYMLSS TVSSKILRAI ALKEGFHFEE TLTGFKWMGN RAKQLIDQGK TVLFAFEEAI GYMCCPFVLD KDGVSAAVIS AELASFLATK NLSLSQQLKA IYVEYGYHIT KASYFICHDQ ETIKKLFENL RNYDGKNNYP KACGKFEISA IRDLTTGYDD SQPDKKAVLP TSKSSQMITF TFANGGVATM RTSGTEPKIK YYAELCAPPG NSDPEQLKKE LNELVSAIEE HFFQPQKYNL QPKAD
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥85% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Maliekal P., et al. (2007) J. Biol. Chem. 282:31844-31851.
USBio References
No references available
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