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350195 PRPS2, Recombinant, Human, aa1-321, His-Tag (Ribose-phosphate pyrophosphokinase 2 isoform 1) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_001034180
Molecular Weight
37.4
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

PRPS2 also known as ribose-phosphate pyrophosphokinase 2 isoform 1. The Protein belongs to the ribose-phosphate pyrophosphokinase family. The Protein catalyzes the synthesis of 5-phosphoribosyl1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.

Source
Recombinant protein corresponding to aa1-321 of human PRPS2, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~37.4kD
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMPNIVLF SGSSHQDLSQ RVADRLGLEL GKVVTKKFSN QETSVEIGES VRGEDVYIIQ SGCGEINDNL MELLIMINAC KIASSSRVTA VIPCFPYARQ DKKDKVGESR APISAKLVAN MLSVAGADHI ITMDLHASQI QGFFDIPVDN LYAEPAVLQW IRENIAEWKN CIIVSPDAGG AKRVTSIADR LNVEFALIHK ERKKANEVDR MVLVGDVKDR VAILVDDMAD TCGTICHAAD KLLSAGATKV YAILTHGIFS GPAISRINNA AFEAVVVTNT IPQEDKMKHC TKIQVIDISM ILAEAIRRTH NGESVSYLFS HVPL
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Mannava S., et al. (2008) Cell Cycle 7 (15), 2392-2400, 2. Tatibana M., et al. (1995) Adv. Enzyme Regul. 35, 229-249.
USBio References
No references available
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