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350273 SDC1, Recombinant, Human, aa18-254, His-Tag (Syndecan-1 precursor) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_002988
Molecular Weight
27
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

Syndecan-1 precursor, also known as SDC1, is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. SDC1 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia.

Source
Recombinant protein corresponding to aa18-254 of human SDC1, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~27kD
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQPALP QIVATNLPPE DQDGSGDDSD NFSGSGAGAL QDITLSQQTP STWKDTQLLT AIPTSPEPTG LEATAASTST LPAGEGPKEG EAVVLPEVEP GLTAREQEAT PRPRETTQLP TTHQASTTTA TTAQEPATSH PHRDMQPGHH ETSTPAGPSQ ADLHTPHTED GGPSATERAA EDGASSQLPA AEGSGEQDFT FETSGENTAV VAVEPDRRNQ SPVDQGATGA SQGLLDRKEV LG
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. O'Connell FP., et al. (2004) Am J Clin Pathol. 121(2):254-63-21531, 2. Rawstron AC., et al. (2006) Curr Protoc Cytom. 6: unit6.23.
USBio References
No references available
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