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351147 CD83, Recombinant, Human, aa20-144, His-Tag|(CD83 antigen Isoform b precursor, BL11, HB15) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_001035370
Molecular Weight
16
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene.

Recombinant protein corresponding to aa20-144 from human CD83, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~16kD (148aa)
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSTPEVKVA CSEDVDLPCT APWDPQVPYT VSWVKLLEGG EERMETPQED HLRGQHYHQK GQNGSFDAPN ERPYSLKIRN TTSCNSGTYR CTLQDPDGQR NLSGKVILRV TGCPAQRKEE TFKKYRAE
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
~0.1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 30% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Zhou LJ, Tedder TF, et al. (1995). J Immunol. 154(8):3821-35.2. Lechmann M, Berchtold S, et al. (2002). Trends Immunol. 23(6):273-5.
USBio References
No references available
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