CD70, Recombinant, Human, aa39-193, His-Tag CAS

Grade

Purified

Swiss Prot

P32970

Molecular Weight

19.1

EU Commodity Code

30021019

Shipping Temp

Blue Ice

Storage Temp

-20°C

CD27 ligand, CD27-L Tumor necrosis factor ligand superfamily member 7, CD70

Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Source

Recombinant protein corresponding to aa39-193 from human CD70, fused to His-Tag at N-terminal, expressed in Yeast.

Molecular Weight

~19.1kD

Amino Acid Sequence

QRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP

Storage and Stability

Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Source

Recombinant, Yeast

Purity

≥90% (SDS-PAGE)

Form

Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor.Goodwin R.G., Alderson M.R., Smith C.A., Armitage R.J., Vandenbos T., Jerzy R., Tough T.W., Schoenborn M.A., David-Smith T., Hennen K., Falk B., Cosman D., Baker E., Sutherland G.R., Grabstein K.H., Farrah T., Giri J.G., Beckmann M.P.Cell 73:447-456(1993).

USBio References

No references available

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372682 CD70, Recombinant, Human, aa39-193, His-Tag (Antigen CD70) CAS:

Grade

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Molecular Weight

EU Commodity Code

Shipping Temp

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CD27 ligand, CD27-L Tumor necrosis factor ligand superfamily member 7, CD70

References

USBio References

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