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374640 PDCD10, Recombinant, Human, aa1-212, His-SUMO-Tag (Programmed Cell Death Protein 10) CAS:

Specifications
References
Grade
Purified
Swiss Prot
Q9BUL8
Molecular Weight
40.7
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15

Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.

Source
Recombinant protein corresponding to aa1-212 from human PDCD10, fused to His-SUMO-Tag at N-terminal, expressed in E. coli.
Molecular Weight
~40.7kD
Amino Acid Sequence
MRMTMEEMKNEAETTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
As Reported
Form
Supplied as a liquid in Tris, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. cDNA cloning and expression of an apoptosis-related gene, human TFAR-15 gene. Wang Y.G., Liu H.T., Ma D.L., Zhang Y.M.Sci. China, Ser. C, Life Sci. 42:323-329(1999).
USBio References
No references available
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