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374672 Pf4, Recombinant, Mouse, aa30-105, His-SUMO-Tag (Platelet Factor 4) CAS:

Specifications
References
Grade
Purified
Swiss Prot
Q9Z126
Molecular Weight
24.2
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
C-X-C motif chemokine 4

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity).

Source
Recombinant protein corresponding to aa30-105 from mouse Pf4, fused to His-SUMO-Tag at N-terminal expressed in E. coli.
Molecular Weight
~24.2kD
Amino Acid Sequence
VTSAGPEESDGDLSCVCVKTISSGIHLKHITSLEVIKAGRHCAVPQLIATLKNGRKICLDRQAPLYKKVIKKILES
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
As Reported
Form
Supplied as a liquid in Tris, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. "Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis." Watanabe O., Natori K., Tamari M., Shiomoto Y., Kubo S., Nakamura Y.J. Hum. Genet. 44:173-176(1999).
USBio References
No references available
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