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T5600-07D Tissue Plasminogen Activator, non-enzymatic, Recombinant, Human (tPA) CAS:

Specifications
References
Grade
Highly Purified
Molecular Weight
70
EU Commodity Code
30021019
Shipping Temp
Dry Ice
Storage Temp
-70°C

Human tPA has the active site mutation S478A, which renders it catalytically inactive. It is >90% single chain and retains exosite binding as well as other properties of wild type tPA. Recombinant, produced in insect cells.

Recombinant corresponding to human tPA expressed in insect cell culture.
Molecular Weight
~70kD
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Source
Recombinant, Insect cells
Purity
≥95% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in 0.4M HEPES, 0.1M sodium chloride, pH 7.4.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
PJ Declerck, M De Mol, DE Vaughan, and D Collen J. Biol. Chem., Jun 1992; 267: 11693 - 11696.
USBio References
No references available
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