Technical Data
0004-02B
4-1 BB Receptor, Recombinant, Human (CD137, 4-1BB Ligand Receptor, TNFRSF9, CDw137, ILA, MGC2172, T-cell antigen 4-1BB homolog)
5ug
20ug
Molecular Biology Storage: -20CShipping: RT
Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Human 4-1BBR is a 17.7kDa protein consisting of 167 amino acid residues.

Source: E. coli

Purity: 98% by SDS-PAGE and HPLC analyses

Endotoxin: 0.1ng/ug (1EU/ug).

Biological Activity: Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC (peripheral blood mononuclear cells). About 90% of inibition was seen using a concentration of 1ug for both 4-1BBL and 4-1BBR.

Reconstitution: We recommend a quick spin followed by reconsitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future use.

Storage and Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20C. Reconstituted 4-1BBL should be stored in working aliquots at -20C.

AA Sequence: MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS

Country of Origin: USA

Molecular Weight:
17.7kDa
Source: E. coli
Form: The sterile ltered solution was lyophilized from 0.3X PBS.

Important Note: This product is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.