Technical Data
0014-01E
14-3-3
Description:
0014-01E recognizes all isoforms of the 14-3-3 protein family. The 14-3-3 family consists of 30kD proteins that are involved in multiple cellular processes including protein kinase signalling pathways, regulation of cell cycle progression, transcription and intracellular trafficking. Protein interactions with 14-3-3 show distinct preferences for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.

Applications:
Suitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry (paraffin). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceSheepRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to all isoforms of sheep 1433.
Purity:
Serum
Form
Supplied as a liquid, 0.09% sodium azide.
Specificity:
Recognizes sheep 1433. Species Crossreactivity: human, bovine, rat, mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Aitken, A et al. (2006) 1433 proteins: A historic overview. Seminars in cancer biology 16:162172.