Technical Data
0014-04C
14-3-3 epsilon (YWHAE, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein, epsilon Polypeptide, 14-3-3E, 14-3-3 Protein epsilon, FLJ45465, FLJ53559, KCIP-1, MDCR, MDS)
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Technical Data |
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0014-04C |
14-3-3 epsilon (YWHAE, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein, epsilon Polypeptide, 14-3-3E, 14-3-3 Protein epsilon, FLJ45465, FLJ53559, KCIP-1, MDCR, MDS) |
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Description: Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Positive Control: Jurkat Cell Lysate. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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