Technical Data
010072
3,3'-Diindolylmethane
1g
|
Technical Data |
|
010072 |
3,3'-Diindolylmethane |
1g |
| Biochemicals | Storage: RTShipping: RT |
|
3,3'-Diindolylmethane is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines. 3,3'-Diindolylmethane is an antiproliferative and inducer of apoptosis; promotes proteasomal degradation of Cdc25C and Cdk1. Inhibits phosphorylation of EGFR and downstream activation of ERK. CAS Number: 1968-05-4 Molecular Formula: C17H14N2 Molecular Weight: 246.31 |
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
|
Kandala, et al.: Mol.Pharmacol., 78, 297 (2010), Kandala, et al.: J. Pharmacol. Exp. Ther., 341 24 (2012),
|
||