		Technical Data
011305	Esterastin	5mg

Biochemicals

Storage: RTShipping: RT

Esterastin is a potent inhibitor of lysosomal acid lipase. Esterastin inhibited the enzyme activity very strongly (IC50, about 80 nM). The inhibition of acid lipase by Esterastin was competitive with respect to the substrate and the inhibition constant for Esterastin was 90 nM. Esterastin was less inhibitory to other lipolytic enzymes, such as pancreatic lipase and carboxylesterase. Thus, Esterastin is a potent new inhibitor of lysosomal acid lipase.

CAS Number:
67655-93-0

Molecular Formula:
C28H46N2O6

Molecular Weight:
506.67

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

Ecsedi, G.G., et al.: Biochem. Internat., 10, 337 (1985); Imanaka, T., et al.: J. Biochem., 94, 1017 (1983);

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.