Technical Data
019840
PK 11195
25mg
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Technical Data |
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019840 |
PK 11195 |
25mg |
| Biochemicals | Storage: RTShipping: RT |
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PK 11195 is a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promotes mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells. CAS Number: 85532-75-8 Molecular Formula: C21H21ClN2O Molecular Weight: 352.86 |
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
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Azarashvili, T. et al.: J. Neurochem., 94, 1054 (2005); Le Fur, G. et al.: Life Sci., 33, 449 (1983); Walter, R.B. et al.:
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