Technical Data
019859
Ponatinib
10mg
Biochemicals Storage: 4CShipping: RT
Ponatinib is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors.

Melting Point:
As reported

Solubility:
As reported

Method for Determining Identity:
Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis

TLC Conditions:
As reported

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive. Store under inert atmosphere.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards:
All products should be handled by qualified personnel only, trained in laboratory procedures.


CAS Number:
943319-70-8

Molecular Formula:
C29H27F3N6O

Molecular Weight:
532.56
Purity: ~90% by HPLC
Form: As Reported
Weisberg, E., et al.: Cancer Cell, 7, 129 (2005), Zhou, T., et al.: Chem. Biol. Drug Des., 70, 171 (2007), Quintas-Cardama, A., et al.: Blood, 2009, 113, 1619 (2009),

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.