		Technical Data
020853	SB-505124	10mg

Biochemicals

Storage: RTShipping: RT

SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less potency. SB-505124 blocks TGF- –induced apoptosis of FaO cells and NRP 154 cells in a concentration-dependent manner. SB-505124 has been shown to suppress the migration and invasion of breast cancer MCF-7-M5 cells.

CAS Number:
694433-59-5

Molecular Formula:
C20H21N3O2

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

Goto, N. et al.: Cancer Sci., 102, 1501 (2011); DaCosta, B.S. et al.: Mol Pharmacol., 65, 744 (2004);

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.