Technical Data
022960
Ziconotide Polyacetate
250ug
Biochemicals Storage: 4CShipping: RT
selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective.

Form:
White Solid

Melting Point:
>190C (dec.)


Solubility:
Methanol

Molecular Formula:
C100H175N35O31S76 xC2H4O2

Molecular Weight:
2556.07
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.
Olivera, B.M., et al.: Biochemistry, 26, 2086 (1987), Barksdale, C.M., et al.: J. Clin. Ligand Assay, 19, 229 (1996), McGuire, D., et al.: J. Cardiovasc. Pharmacol., 30, 400 (1997), Staats, P.S., et al.: J. Am. Med. Assoc., 291, 63 (2004),

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.