		Technical Data
029714	Acvr1c (Activin Receptor Type-1C, Activin Receptor Type IC, ACTR-IC, Activin Receptor-like Kinase 7, ALK-7, Alk7)

Description:
ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Mouse	Rabbit

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to aa155 from mouse ALK-7.

Purity:

Purified by affinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.

Specificity:

Recognizes mouse ALK-7. Species Crossreactivity: human and rat.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.