Technical Data
029954
ANXA1 (Annexin A1)
Description:
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of ~35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40kD, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:10,000
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG113B32Purified
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Purified recombinant protein corresponding to a fragment of human ANXA1 (aa144-248), expressed in E.coli.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.05% sodium azide, 0.5% protein stabilizer.
Specificity:
Recognizes human ANXA1, Mr 38.7kD. Species Crossreactivity: mouse, monkey
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Cancer Lett. 2010 Aug 1;294(1):111-7. 2.Pathology. 2010 Jan;42(1):43-9.