Technical Data
030784
APOA1, NT (APOA1, Apolipoprotein A-I, Apolipoprotein A1, Truncated apolipoprotein A-I, Apolipoprotein A-I(1-242))
Description:
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100~250

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG1464CT10.4.4Affinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
APOA1 Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the N-term region of human APOA1.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Clemente-Postigo, M., et al. Clin. Biochem. 43 (16-17), 1300-1304 (2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010)
Dawar, R., et al. Am. J. Clin. Pathol. 134(2):249-255(2010)
Mattei, J., et al. Nutr Metab Cardiovasc Dis (2010) In press
Bencharif, K., et al. Lipids Health Dis 9, 75 (2010)