Technical Data
030787
ARSA, CT (ARSA, Arylsulfatase A, Cerebroside-sulfatase, Arylsulfatase A component B, Arylsulfatase A component C)
Description:
ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this protein lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100~250

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a498CT24.1.2Affinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
ARSA Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the C-term region of human ARSA.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Cesani, M., et al. Hum. Mutat. 30 (10), E936-E945 (2009) Matzner, U., et al. J. Biol. Chem. 284(14):9372-9381(2009) Bisgaard, A.M., et al. Clin. Genet. 75(2):175-179(2009) Lugowska, A., et al. Clin. Genet. 75(1):57-64(2009) Oshikawa, M., et al. Mol. Vis. 15, 482-494 (2009)